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EPC Endothelial Progenitor Cells

Endothelial progenitor cells (EPC) are immature cells present in the blood, where their physiological role is the maintenance of vascular integrity. They are derived from bone marrow, then enter in the blood, where they constitute a rare population of cells. They are integrated in the formation of new vessels, for example during the process of revascularization following a vascular lesion. In culture, these cells form colonies of endothelial cells, which quickly acquiring a strong power of proliferation. EPCs can be isolated from umbilical cord blood, where their number is about 10 times higher than that of adult peripheral blood, and they have a greater proliferation than that isolated from adult peripheral blood. They express all the classical endothelial cell markers (CD31, CD144, KDR, vWF).

These endothelial cells derived from EPC have several advantages:

  1. Their capacity to proliferate is higher than that of HUVEC (Human Umbilical Vein Endothelial Cells)
  2. They are stable in culture
  3. They have not undergone a process of specialization for example arterial or venous, because they are derived from immature progenitors
  4. They have all the functions of endothelial cells.

Each batch of cells produced by us comes from a single donor. The number of cells in our standard packaging is 500,000 cells guaranteed at passage 3 after thawing in your laboratory. All our batches are subjected to high quality controls allow us to guarantee you efficient cells after thawing. Each batch is tested by an independent laboratory, and, is negative for HIV-1/2, hepatitis B and hepatitis C. A detailed technical sheet for each batch produced is provided.

 

Our internal R&D allows us to continuously improve our production, such as, for example, an optimized freezing process for a better cell viability. The routing and delivery deadlines of your package are important as for the quality of our cells. special attention is therefore brought to our logistics to guarantee you efficient cells.

Each experience, each client is unique. You need more early passages? A different packaging? Expert in the field of vascular biology, we can advise you and provide you with solutions.

ABCell-Bio only guarantees the performance of its cells when grown under recommended conditions.

WARNING: These cells are intended for scientific use only; not for medical, human or veterinary purposes.

EPC Endothelial Progenitor Cells

More informations

Reference EPC-CT-CG
Applications Angiogenesis - Inflammation - Oncology - Pharmacology
Caracteristics 500 000 cells cryopreserved - single donor - Passage 3 Phenotypical (CD31, CD144, KDR, vWF) and functional characterizations of the cells
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