+ 33 1 42 80 19 08
contact@abcell-bio.com

Our Activity

At ABCell-Bio, we share this vision; we are convinced that behind any success there has been, before all, advice, collaboration and trust.

 

Specialized in the isolation and the culture of characterized primary human cells, the ABCell-Bio team has been offering you for over ten years all its bio-expertise in fields as complex as Hematopoiesis, Vascular Biology, and Tissue Regeneration.

 

Our commitment ? To offer you high quality products associated with scientific and technical support.

Enthusiastic scientists, we are dedicated to help you meet your milestones and your deadlines.

 

Our team of multidisciplinary experts possesses the know-how and the requested flexibility to study jointly your needs in cellular biology, even the most specific ones and to set up with you tailor-made solutions.

 

In strict compliance with ethical standards, ABCell-Bio develops and improves continuously its processes in order to ensure that you benefit from products and services which meet your requirements.

Hematopoiesis

Hematopoiesis refers to the set of physiological mechanisms involved in the production of blood cells or components.


Hematopoietic stem cells (HSCs) are the starting point of this hematopoiesis process.


They ensure the permanent production of all the different blood cell lines, allowing them to be constantly renewed. The hematopoietic stem cells can differentiate into myeloid and lymphoid precursors.

 

Hematopoietic stem cells are not identifiable by their morphology, but they are defined by several surface markers, such as CD34 or CD133. These different phenotypic markers are used for the identification and purification of the HSC population.


In adults, hematopoiesis takes place in the bone marrow, where hematopoietic stem cells establish the effective hematopoietic niche; they are also presents in the peripheric blood, but in smaller quantities.

 

Hematopoietic stem cells can also be of fetal origin, they are localized in umbilical cord blood, or placental blood. This alternative cellular source has the advantage of low immunogenicity, linked to the immaturity of the fetal immune system.

 

By their multipotency, their graft, their cytokines sensibility and their origin characteristic, hematopoietic stem cells are studied and are the subject of research in different fields as cancerology, cell therapy, aging, immunology...

At ABCell-bio, we are recognized in this field by our catalog of progenitors of interest, and, to provide satisfaction to our customers on the quality of our cells.

Vascular Biology

The study of Vascular Biology is one of the pillars of our activity. Extensive subject with several applications, endothelial cells play different roles thus conferring the endothelium the status of dynamic and multifunctional organ.

 

Our experts possess recognized expertise in the isolation and culture of primary endothelial cells present in umbilical cord and cord blood.

 

Used in many pharmacology and research studies on angiogenesis, atherosclerosis, inflammation, immunity, oncology..., our endothelial cells are the subject to rigorous controls handing you over the most powerful tools to meet all your needs.

Tissue Regeneration

Tissue regeneration represents a major challenge in terms of both scientific knowledge and medical advances. The regeneration process is possible in particular thanks to mesenchymal stem cells (MSC), which combine stemness and support functions.

 

Mesenchymal stem cells are multipotent. They also can differentiate into a wide variety of cell types and have the ability to self-renew. The aim of many studies is to better understand the mechanisms of tissue regeneration, and in particular the role of these mesenchymal stem cells (MSC). Several studies show that the ability and the diversity of mesenchymal stem cell differentiation are different according to the origin of the tissue they are extracted from.

 

In view of their characteristics, MSC are tools with multiple applications, as regenerative medicine, tissue engineering, immunomodulation, or as research topics in development, stem cells...

 

Regardless on the quality of your research, our experts offer you a range of competent MSCs from various tissue sources. Our cells are all tested in vitro on their ability to clonogenicity, and differentiation into adipocytes, chondrocytes, and osteoblasts.

Our commitment ? To offer you high quality products associated with scientific and technical support.